Genome Analysis and Characterization of Vibrio parahaemolyticus Isolated from Mussels
최효주*·정현경1·진현우·정상현·김영삼1·신순범·하광수
국립수산과학원 식품위생가공과, 1국립수산과학원 생명공학과
Vibrio species are globally well-established as significant foodborne pathogens. These halophilic bacteria inhabit marine environments and pose risks to both marine ecosystems and human health. Vibrio parahaemolyticus is a leading cause of foodborne illness in humans, primarily through the consumption of contaminated seafood, and is associated with various virulence factors. Additionally, the presence of antibiotic resistance genes constitutes a significant risk factor. This study presents a comprehensive genomic analysis of the V. parahaemolyticus VP2406_85 strain isolated from mussels using next-generation sequencing to identify functional genes and proteins. The genome of the VP2406_85 strain comprises 5,299,256 bp and encompasses the virulence genes tdh, trh, and blaCARB-43, the latter of which encodes β-lactamase, a protein associated with antibiotic resistance. Genomic analysis highlighted the presence and variability of genes and traits that potentially contribute to pathogenicity and antimicrobial resistance. These characteristics of V. parahaemolyticus VP2406_85 provide valuable insights into its pathogenic profile, aiding in the development of improved strategies for food safety and public health surveillance.
Vibrio parahaemolyticus, Food safety, Virulence factor, Antimicrobial resistance, Genome