OPEN ACCESS plSSN : 0374-8111 | elSSN : 2287-8815
OPEN ACCESS plSSN : 0374-8111elSSN : 2287-8815
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kfas, vol. 58, no. 4, pp.418-425, August, 2025 DOI. https://doi.org/10.5657/KFAS.2025.0418

Genome Analysis and Characterization of Vibrio parahaemolyticus Isolated from Mussels

최효주*·정현경1·진현우·정상현·김영삼1·신순범·하광수
국립수산과학원 식품위생가공과, 1국립수산과학원 생명공학과

  • ABSTRACT

    Vibrio species are globally well-established as significant foodborne pathogens. These halophilic bacteria inhabit marine environments and pose risks to both marine ecosystems and human health. Vibrio parahaemolyticus is a leading cause of foodborne illness in humans, primarily through the consumption of contaminated seafood, and is associated with various virulence factors. Additionally, the presence of antibiotic resistance genes constitutes a significant risk factor. This study presents a comprehensive genomic analysis of the V. parahaemolyticus VP2406_85 strain isolated from mussels using next-generation sequencing to identify functional genes and proteins. The genome of the VP2406_85 strain comprises 5,299,256 bp and encompasses the virulence genes tdh, trh, and blaCARB-43, the latter of which encodes β-lactamase, a protein associated with antibiotic resistance. Genomic analysis highlighted the presence and variability of genes and traits that potentially contribute to pathogenicity and antimicrobial resistance. These characteristics of V. parahaemolyticus VP2406_85 provide valuable insights into its pathogenic profile, aiding in the development of improved strategies for food safety and public health surveillance.

  • Keyword

    Vibrio parahaemolyticus, Food safety, Virulence factor, Antimicrobial resistance, Genome